Constrained Principal Component Analysis

Download Constrained Principal Component Analysis (fMRI-CPCA) software for multivariate analysis of fMRI data.

Lavigne, K.M., Menon, M., Moritz, S. & Woodward, T.S. (2020). Functional brain networks underlying evidence integration and delusional ideation. Schizophrenia Research,doi:10.1016/j.schres.2019.11.038. PDF

Lavigne, K.M., Menon, M. & Woodward, T.S. (2020). Functional brain networks underlying evidence integration and delusions in schizophrenia. Schizophrenia Bulletin, 46(1):175-183. doi:10.1093/schbul/sbz032. PDF

Luk, J., Underhill, K. & Woodward, T. S. (2018). Psychotic symptoms predicting evidence integration in schizophrenia: A multivariate analysis of the BADE Task. Zeitschrift für Psychologie, 226(3):174–181. PDF

Lavigne, K.M. & Woodward, T.S. (2018). Hallucination and speech-specific hypercoupling in frontotemporal auditory and language networks in schizophrenia using combined task-based fMRI data: An fBIRN study. Human Brain Mapping, 2018(39):1582–1595. PDF

Goghari, V.M., Sanford, N., Spilka, M.J., & Woodward, T.S. (2017). Task-related functional connectivity analysis of emotion discrimination in a family study of schizophrenia. Schizophrenia Bulletin, 43(6):1348–1362. PDF

Sanford, N. & Woodward, T.S.  (2017). Symptom-related attributional biases in schizophrenia and bipolar disorder.  Cognitive Neuropsychiatry, 22(4):263-279. PDF

Larivière, S., Lavigne, K.M.,  Woodward, T.S., Gerretsen, P., Graff-Guerrero, A., & Menon, M.  (2017). Altered functional connectivity in brain networks underlying self-referential processing in delusions of reference in schizophrenia.  Psychiatry Research: Neuroimaging, 263 (2017): 32–43. PDF

Woodward, T.S., Leong, K., Sanford, N., Tipper, C.M., & Lavigne, K.M. (2016). Altered balance of functional brain networks in schizophrenia. Psychiatry Research: Neuroimaging, 248 (2016): 94-104. PDF

Whitman, J.C., Takane, Y., Cheung, T.P.L., Moiseev, A., Ribary, U., Ward, L.M., & Woodward, T.S. (2016). Acceptance of evidence-supported hypotheses generates a stronger signal from an underlying functionally-connected network. NeuroImage, 127 (2016): 215–226. PDF

Woodward, T.S., Tipper, C.M., Leung, A., Lavigne, K.M., Sanford, N., Metzak, P.D.  (2015).  Reduced functional connectivity during controlled semantic integration in schizophrenia: a multivariate approach.  Human Brain Mapping, 36: 2948-2964 (2015). PDF

Metzak, P.D., Lavigne, K.M., & Woodward, T.S.  (2015).  Functional brain networks involved in reality monitoring. Neuropsychologia 75(2015) : 50-60. PDF

Lavigne, K.M., Metzak, P.D., & Woodard, T.S.  (2015).  Functional brain networks underlying detection and integration of disconfirmatory evidence.  NeuroImage 112(2015): 138-151. PDF

Lavigne, K.M., Rapin, L.A., Metzak, P.D., Whitman, J.C., Jung, K., Dohen, M., Loevenbruck, H., &Woodward, T.S. (2015).  Left-dominant temporal-frontal hypercoupling in schizophrenia patients with hallucinations during speech perception.  Schizophrenia Bulletin, 41(1): 259-267. PDF

Hyman, J.M., Whitman, J., Emberly, E., Woodward, T.S., & Seamans, J.K.  (2014).  Action and outcome activity state patterns in the anterior cingulate cortex.  Cerebral Cortex, 23:1257-1268. PDF

Raineki, C., Hellemans, K.G.C., Bodnar, T., Lavigne, K.M., Ellis, L., Woodward, T.S., & Weinberg, J.  (2014).  Neurocircuitry underlying stress and emotional regulation in animals prenatally exposed to alcohol and subjected to chronic mild stress in adulthood.  Frontiers in Endocrinology, 5(5): 1-14. PDF

Lavigne, K.M., Rapin, L.A., Metzak, P.D., Whitman, J.C., Jung, K., Dohen, M., Loevenbruck, H., &Woodward, T.S. (2014).  Left-dominant temporal-frontal hypercoupling in schizophrenia patients with hallucinations during speech perception.  Schizophrenia Bulletin, doi:10.1093/schbul/sbu004. PDF

Whitman, J.C., Metzak, P.D., Lavigne, K.M., & Woodward, T.S. (2013). Functional connectivity in a frontoparietal network involving the dorsal anterior cingulate cortex underlies decisions to accept a hypothesis. Neuropsychologia, 51(2013):1132–1141. PDF

Woodward, T.S., Feredoes, E., Metzak, P.D., Takane, Y., & Manoach, D.S. (2013). Epoch-specific functional networks involved in working memory. NeuroImage, 65: 529-539. PDF

Lavigne, K.M., Hofman, S., Ring, A.J., Ryder, A.G., & Woodward, T.S. (2013). The personality of meaning in life: Associations between dimensions of life meaning
and the Big Five. The Journal of Positive Psychology, 8(1): 34-43. PDF

Rapin, L.A., Dohen, M., Loevenbruck, H., Whitman, J.C., Metzak, P.D., Woodward, T.S.  (2012).  Hyperintensity of functional networks involving voice-selective cortical regions during silent thought in schizophrenia.  Psychiatry Research: Neuroimaging. 202(2012): 110-117PDF

Metzak, P.D., Riley, J., Wang, L., Whitman, J.C., Ngan, E.T.C. & Woodward, T.S. (2012). Decreased efficiency of task-positive and task-negative networks during working memory in schizophrenia. Schizophrenia Bulletin. 38(4), 803-813.   PDF  

Metzak, P.D., Feredoes, E., Takane Y., Wang, L., Weinstein, S., Cairo, T., Ngan, E.T.C, & Woodward, T. S. (2011). Constrained principal component analysis reveals functionally connected load-dependent networks involved in multiple stages of working memory. Human Brain Mapping, 32(6), 856-871.  PDF  

Woodward, T. S., Cairo, T. A., Ruff, C. C., Takane, Y., Hunter, M.A. & Ngan, E.T.C. (2006). Functional connectivity reveals load dependent neural systems underlying encoding and maintenance in verbal working memory. Neuroscience, 139(1), 317-325.   PDF